Virtual Conference
Prof. Hanaa Banjar

Prof. Hanaa Banjar

King Faisal Specialist Hospital and Research Center, KSA

Title: Chronic complications of cystic fibrosis patients in a tertiary care center in Saudi Arabia


Introduction: Cystic Fibrosis (CF) is a common disease in the Middle East. A complete and a comprehensive study of the most chronic complications of CF is lacking or scarce. 

Objectives: To highlight the most common complications of CF patients in the largest CF center in Saudi Arabia.

Material and method: A retrospective chart review of all confirmed CF patients from the period 1993-2018

Results: A total of 430 confirmed CF patients, 49.54% patients are males, and 50.46% are females. Around 94% were of consanguineous marriages, 45% had family history of CF. Multiple chronic complications have been encountered in the care of this group: (11%) of patients were confirmed to have Meconium Ileus, (3%) revealed to have a gall bladder stones, 2 patients required cholecystectomy. Pancreatitis was found in (2%). (56%) had elevated liver enzymes:  AST in (36%), elevated alkaline phosphatase (ALP) in (49.1%), elevated GGT in (23%), and elevated bilirubin in (7%). (12%) have Diabetes mellitus that detected as early as 3 years of age. (72%) who had first sample Vit A level measured were Vit A deficient. (81%) patients had vitamin D deficiency. (31%) had Vit E deficiency. (23%) had Vit K deficiency. Follow up samples of ADEK vitamins showed persistence of deficiency between 36 - 81% despite supplementation for 4 - 7 years’ period. There is a persistent increase in the prevalence of the common bacteria over the follow-up period of 7 years, namely Hemophilus influenzae (H. influenzae), Staphylococcus aureus (S. aureus), and all Pseudomonas (P. aeruginosa) culture types. Comparing cultures from the first and last follow-up visits, there was an increase in the prevalence of all (P. aeruginosa) cultures from (34%) to (53%), and a decrease in the prevalence of (S. aureus) and (H. influenzae) during the same follow-up period. (11%) were positive for MRSA,

Conclusion: CF is a common disease in Saudi Arabia. Chronic complications of the disease required multiple disciplinary team and affected their median survival. 


Hanaa Banjar is a professor of pediatrics at Alfaisal University, Riyadh since 2013, She is also a consultant pediatric pulmonology and the director of pediatric pulmonology fellowship program at King Faisal Specialist Hospital and Research Center, Riyadh. She received her residency in pediatrics from the University of Ottawa, Ontario, Canada and her pulmonary fellowship from McGill University, Montreal, Quebec, Canada. As an expert in pediatric pulmonary medicine, especially in cystic fibrosis, pulmonary hypertension, and Non-CF Bronchiectasis, she serves as the principle investigator of the cystic Fibrosis registry of up to 400 patients and the principle author of 90 articles.