Background: The most typical skin condition that affects adolescents and adults is acne. The most frequently recommended antibiotic for treating acne vulgaris was Minocycline. Due to major concerns regarding its safety, including skin pigmentation, which can sometimes be irreversible, it has been used less in recent years. 

Objective: The aim of the was to evaluate the efficacy and safety of Minocycline for the treatment of acne vulgaris in adult patients. Methods: This cross-sectional study was conducted at tertiary care hospital Dhaka District from June 2021 to July 2022. Minocycline was prescribed to 30 adult patients (3 men and 27 women) to treat their acne vulgaris were enrolled in the study to determine the drug's effectiveness and safety. In moderate cases and severe cases, the prescribed doses of Minocycline were 50 mg and 100 mg, respectively. The average treatment time was 3 months. Every one month the patients were rechecked to assess their post-treatment progress and side effects. 

Results: The clinical evaluation of the severity of each patient's acne revealed that according to severity of cases, 15(50.0%) had moderate, 6(20.0%) had moderately severe and 9(30.0%) had severe acne problem and 9 patients (30.0%) reported experiencing side effects. The only significant side effects were pigmentation occurred in 1.2–3.6% of cases, and patients receiving higher doses of minocycline for longer periods of time were noticeably more likely to have it. 

Conclusion: Although there is evidence that Minocycline is effective in treating moderately to mildly severe inflammatory acne vulgaris, there is still no proof that it is superior to other widely used treatments. Concerns still exist regarding its safety due to various side effects.

Farzana Afroz is a reputed Dermatologist in the country with more than 20 years of experience in the field of Dermatology Venereology. She was born in 11th December 1979. She started her educational life at Faizunnesa Govt. Girls High School, Comilla and completed her S.S.C in 1995. She completed her Higher secondary school certificate from Carmichael College, Rangpur successfully in 1997. She completed MBBS successfully in 2004 from M.A. Rahim Medical College, Dinajpur. She also completed her MCPS in Skin and VD from Bangladesh College of Physicans and Surgeons in July, 2013. After that, she obtained FCPS in Skin and VD from Bangladesh College of Physicans and Surgeons in January, 2015. Currently, she was working as Associate Professor in Medical College for Women & Hospital, Uttara, Dhaka. After she worked as Associate Professor (C.C.) in International Medical College & Hospital, Tongi, Gazipur. She also worked as Assistant Professor in Nightingale Medical College & Hospital, Ashulia, Dhaka. After that she joined as a Junior Consultant in Laser Treat, Dhaka. In addition, she was working as Consultant Dermatologist in Ahsania Mission Cancer & General Hospital, Uttara, Dhaka. After that she worked as a Lecturer cum Medical Officer in the Dept. of Pathology, Medical College for the Women & Hospital Uttara, Dhaka. She also worked as a Lecturer in Monsur Ali Medical College & Hospital, Uttara, Dhaka. She has completed her fellowship in Laser Surgery, Chemical Peel & Cosmetic Dermatology, India. She is professionally experienced in Hands on training on Filler, Botox, Thread lift & Dermoscopy. She has a 2 years training in Dermatology & Venereology from BSMMU & Shaheed Suhrawardi Medical College, Dhaka. She has a 1-year experience in training in Internal Medicine from Shaheed Suhrawardi Medical College, Dhaka. She also completed l year course successfully in Dermatology & Venereology from BSMMU. She is a professional, enthusiastic, honest and dermatologist. She has some national and international publications which reflects her contributions to the field of Skin and Dermatology Venereology.