Dr. Shivani VermaSafdarjung Hospital, India
Title: Left ventricular function and n-terminal pro b-type natriuretic peptide levels in women with hypertensive disorders of pregnancy: A prospective observational study
A prospective observational case-control study was conducted between 2018 to 2020 in an Indian tertiary care hospital and included antenatal women beyond 20 weeks of gestation with 160 women with HDP as cases and 160 normotensive women as controls. Echocardiography was performed to assess left ventricular structure and function. Quantitative analysis of NT-pro BNP levels was performed based on fluorescence immunochromatography.
Women with HDP were observed to have a significant difference in the value of Left ventricular structure and function with a p-value <0.0001. Mild systolic dysfunction was observed in 8.1% of the women in the HDP group (20% of women with severe preeclampsia and 33.3% of eclamptic women). A significantly lower value of Left ventricular ejection fraction (LVEF) and higher values of NT-pro BNP was observed in women with HDP who developed maternal complications and had adverse neonatal outcomes (p<0.001). Echocardiography and NT-pro BNP levels can be used routinely in women with severe forms of HDP to detect early signs of cardiac dysfunction.
Shivani Verma has completed her MS, DNB OBGYN from Safdarjung Hospital, New Delhi, India, and is currently working as a Senior Resident. She is an active member of various societies dealing with women’s health issues and has been involved in various academic activities and conferences. She has a keen interest in high-risk pregnancies and infertility. She has participated as a moderator in panel discussions and has presented research papers and case reports at various national and international conferences.